2. Signaling Pathways
  3. Epigenetics
  4. Epigenetic Reader Domain
  5. Epigenetic Reader Domain Isoform
  6. Epigenetic Reader Domain Agonist

Epigenetic Reader Domain Agonist

Epigenetic Reader Domain Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-151527
    PI3K/Akt/CREB activator 1
    		Agonist 98.64%
    PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD).
  • HY-176056
    Hedgehog IN-9
    		Agonist
    Hedgehog IN-9 (Compound 1) is a Hedgehog inhibitor. Hedgehog IN-9 prevents GLI1 expression and enhances cellular BRD2 protein levels. Hedgehog IN-9 inhibits growth of medulloblastoma spheroid cells and can be used for synthesis of photoaffinity labeling probe.